5 Key PCOS Supplements you need
Looking for the best PCOS supplements? Look no further. I know firsthand how overwhelming it can be to sift through all the advice out there. But after years of trial and error, research, and working with natural methods, I’ve found that these PCOS supplements play a crucial role in managing PCOS.
Of course, supplements aren’t a magic fix—but when combined with the right diet, exercise, and lifestyle changes, they can make a huge difference.
Here are five key PCOS supplements that have been backed by science and have personally helped me (and many others) take control of PCOS symptoms.

1. Inositol – Balancing Blood Sugar & Supporting Ovulation
If you’ve spent any time researching PCOS supplements, you’ve probably heard about inositol. This B-vitamin-like compound is one of the most researched supplements for PCOS, particularly for its ability to improve insulin resistance and ovulatory function.
According to the publication Human Reproduction Update, inositol, particularly myo-inositol and D-chiro-inositol, helps restore ovarian function and improve egg quality in women with PCOS. Research suggests that taking inositol can lead to more regular periods, improved fertility, and better insulin sensitivity (source).
Benefits of Inositol for PCOS:
- Improves insulin sensitivity and reduces insulin resistance
- Supports ovulation and menstrual cycle regulation
- May help with weight management
- Reduces symptoms of hormonal acne
Best Inositol Supplements
Ovasitol by Theralogix – A high-quality inositol supplement with a recommended 40:1 ratio of myo-inositol to D-chiro-inositol

Wholesome Story Myo & D-Chiro Inositol – A budget-friendly alternative with the ideal ratio for PCOS support. You can find it in Powder form or Supplement Tablet Form.

2. Curcumin – Powerful Anti-Inflammatory Support
Curcumin, the active compound in turmeric, is a powerhouse anti-inflammatory. Since chronic inflammation is one of the root causes of PCOS symptoms, reducing inflammation can help balance hormones, support digestion, and even aid in weight loss.
According to the publication Nutrients, curcumin has been shown to lower testosterone levels and reduce markers of inflammation in women with PCOS, which can help with acne, bloating, and metabolic health (source).
Benefits of Curcumin for PCOS:
- Reduces swelling, bloating, and inflammation
- Supports hormonal balance and may help lower testosterone
- Aids in digestive health
Best Curcumin Supplements
1.THORNE Curcumin Phytosome 1000 mg
2. NatureWise Curcumin Turmeric
3. Coenzyme Q10 (CoQ10) – Boosts Energy, Fertility & Weight Loss
PCOS can leave you feeling exhausted, struggling to lose weight, and dealing with fertility issues. This is where CoQ10 comes in. Coenzyme Q10 is an antioxidant that helps support mitochondrial function, which means it improves how your body produces energy at a cellular level.
According to the publication Reproductive Biology and Endocrinology, supplementing with CoQ10 has been shown to boost egg quality, support metabolism, and help with weight loss in women with PCOS (source).
Benefits of CoQ10 for PCOS:
- Increases energy levels and reduces fatigue
- Supports weight loss and metabolism
- Improves egg quality and fertility
Best CoQ10 Supplements
Doctor’s Best Q10 – High-absorption formula, ideal for energy support
THORNE CoQ10 – A more affordable, effective option
4. Omega-3 – Reduces Belly Fat & Lowers Testosterone
One of the biggest struggles with PCOS is hormonal imbalance, which often leads to higher testosterone levels. This can result in acne, excessive hair growth (hirsutism), and weight gain around the belly. Omega-3 fatty acids, especially EPA and DHA, help lower testosterone levels, reduce inflammation, and improve metabolic function.
According to the publication The American Journal of Clinical Nutrition, omega-3 supplementation has been shown to reduce insulin resistance, lower testosterone, and support heart health in women with PCOS (source).
Benefits of Omega-3 for PCOS:
- Lowers testosterone levels and reduces hormonal acne
- Supports weight loss, especially belly fat
- Improves energy levels and reduces fatigue
Best Omega-3 Supplements
Nordic Naturals Ultimate Omega – High-quality fish oil with a potent dose of EPA & DHA

Viva Naturals Omega-3 Fish Oil – Affordable and high-strength formula
5. Vitamin D – Essential for Insulin Sensitivity
Vitamin D deficiency is incredibly common in women with PCOS, and yet, it plays a crucial role in managing symptoms. This essential vitamin improves insulin sensitivity, hormone regulation, and immune function.
According to the publication Clinical Endocrinology, supplementing with vitamin D can improve insulin resistance and support reproductive health in women with PCOS (source).
Benefits of Vitamin D for PCOS:
- Improves insulin sensitivity and blood sugar regulation
- Supports immune function and reduces inflammation
- Helps regulate menstrual cycles
Best Vitamin D Supplements
NatureWise Vitamin D3 5000 IU – High-potency vitamin D for optimal absorption
Garden of Life Vitamin D3 – Organic, plant-based option with added probiotics

Taking control of PCOS isn’t about finding a quick fix—it’s about long-term, sustainable changes. Supplements can be a game changer when it comes to improving insulin resistance, hormone balance, and overall well-being.
If you’re new to supplements, start with one or two that address your specific symptoms and work from there. As always, talk to your healthcare provider before starting any new supplement regimen.
Which PCOS supplements have worked for you? Let’s chat in the comments!

